Hydrochloric Acid → HCID 67589520, Verbindung

HRID 1416722

Reaktionsgleichung

Reaktionsgleichung von HRID 1416722
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]([OH:29])[CH2:9][NH:10][CH:11]([CH3:28])[CH2:12][C:13]2[CH:27]=[CH:26][C:16]3[O:17][C:18]([C:23]([OH:25])=[O:24])([C:20]([OH:22])=[O:21])[O:19][C:15]=3[CH:14]=2)[CH:5]=[CH:6][CH:7]=1.[C:30]1([CH2:36][CH2:37]O)[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1.Cl>>[ClH:1].[CH2:37]([O:24][C:23]([C:18]1([C:20]([O:22][CH2:9][CH2:8][C:4]2[CH:5]=[CH:6][CH:7]=[CH:2][CH:3]=2)=[O:21])[O:17][C:16]2[CH:26]=[CH:27][C:13]([CH2:12][CH:11]([NH:10][CH2:9][CH:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=3)[OH:29])[CH3:28])=[CH:14][C:15]=2[O:19]1)=[O:25])[CH2:36][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 60542-PhenylethanolHCID 42813555-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylic acid

Produkt 1

HCID 67589520HCID 67589520, Verbindung

Versuchsvorschrift

The title compound was prepared from 5-{2-[2-(3-chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylic acid and 2-phenylethanol accord-ing to the procedure of Example 1 as a colorless oil; 1H NMR (300 MHz, CDCl3): d 1.30-1.45 (brs, 3H), 2.80-2.90 (brm, 1H), 2.89 (t, J=6.9 Hz, 4H), 3.10-3.30 (brm, 2H), 3.39-3.69 (brm, H), 4.40 (t, J=6.8 Hz, 4H), 5.45-5.61 (brs, 2H), 6.70-6.91 (brm, 3H), 7.10-7.35 (complex m, 13H), 7.40-7.51 (brs, 1H), 8.60-8.85 (brs, 1H), 9.91-10.20 (brs, 1H); MS (ES) m/z (relative intensity): 630 (M+ -HCl, 40), 144 (100).

Quellen und Nachweise

ORD-Eintrag
ord-47e1dc4ace2a4cf7af026fa78626eee6
Quelldatensatz
uspto-grants-1999_06
Patentnummer
US05914339

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