Methyl chloroformate → Ethyl 3-[3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphth-2-yl]propiolate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Methyl chloroformate	HCID 6586	—
Edukt	Ethyl 3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphth-2-yl)propiolate	HCID 11000580	—
Edukt	1,1,4,4,7-Pentamethyl-6-ethynyl-1,2,3,4-tetrahydronaphthalene	HCID 11806387	—
Edukt	Butyllithium	HCID 178418339	—
Produkt	Ethyl 3-[3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphth-2-yl]propiolate	HCID 18357952	—

Reaktionsschritte

Employing the same general procedure as used for the preparation of ethyl 3-[5,5,8,8,-tetramethyl-5,6,7,8-tetrahydronaphth-2-yl]propiolate (Compound A), but instead using 1.9 g of (3-methyl-5,5,8,8,-tetramethyl-5,6,7,8-tetrahydronaphth-2-yl)ethyne, 940 mgs (10 mmols) of methylchloroformate and 8.8 mmols of n-butyllithium the title compound was obtained as an oil.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05917082
Quelldatensatz	uspto-grants-1999_06
ORD ID	ord-9c09ec9fb476447bb20881ff7a114314
Quellennotiz	uspto-grants-1999_06