Cyclohexylbenzene → 4-Cyclohexylbenzene-1-sulfonyl chloride

HRID 1417296

Reaktionsgleichung

Reaktionsgleichung von HRID 1417296
[C:1]1([CH:7]2[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:13][S:14](O)(=[O:16])=[O:15].[Cl-].[NH4+]>C(Cl)Cl>[CH:1]1([C:7]2[CH:12]=[CH:11][C:10]([S:14]([Cl:13])(=[O:16])=[O:15])=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Komponenten

5

Edukt 3

HCID 13229CyclohexylbenzeneHCID 24638Chlorosulfonic acidHCID 25517Ammonium Chloride

Produkt 1

HCID 43394424-Cyclohexylbenzene-1-sulfonyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Reaktionsbedingungen

Temperatur
5 °C

Versuchsvorschrift

A solution of 10.6 ml of phenylcyclohexane in 100 ml of methylene chloride was added at 5° C. within 30 minutes to 13.8 ml of chlorosulfonic acid. The mixture was stirred at 5° C. for 1 hour, poured into 400 ml of a 20% ammonium chloride solution and extracted twice with 300 ml of methylene chloride each time. The organic phases were combined, dried with magnesium sulphate and the solvent was removed on a rotary evaporator. 13.6 g of 4-cyclohexyl-benzenesulfonyl chloride separated as a reddish oil, which was used without further purification.

Aufarbeitung

  1. extractionextracted twice with 300 ml of methylene chloride each time
  2. dry with materialdried with magnesium sulphate
  3. customthe solvent was removed on a rotary evaporator
  4. custom13.6 g of 4-cyclohexyl-benzenesulfonyl chloride separated as a reddish oil, which
  5. customwas used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-50e0745eb0ae4b8cb298c4bbbb30b492
Quelldatensatz
uspto-grants-1999_03
Patentnummer
US05877193

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