Acetaldehyde → Acetaldehyde 4-methoxyphenylhydrazone

HRID 1417414Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1417414
Cl.[CH3:2][O:3][C:4]1[CH:9]=[CH:8][C:7]([NH:10][NH2:11])=[CH:6][CH:5]=1.[OH-].[Na+].[CH:14](=O)[CH3:15]>C1(C)C=CC=CC=1>[CH3:2][O:3][C:4]1[CH:9]=[CH:8][C:7]([NH:10][N:11]=[CH:14][CH3:15])=[CH:6][CH:5]=1

Komponenten

5

Edukt 3

HCID 177AcetaldehydeHCID 14798Sodium HydroxideHCID 27239044-Methoxyphenylhydrazine hydrochloride

Produkt 1

HCID 67504694Acetaldehyde 4-methoxyphenylhydrazone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel3×

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

Combine (4-methoxyphenyl)-hydrazine hydrochloride salt (10 g, 57 mmol), sodium hydroxide solution (50 mL, 1M), and extract with toluene. Dry the organic layer over MgSO4, filter, and evaporate in vacuo to give a residue. Combine the residue and toluene (50 mL) and cool to 0° C. Add acetaldehyde (3.5 mL, 63 mmol) dropwise as a solution in toluene (10 mL). When the addition is complete, warm to ambient temperature. After 1 hour at ambient temperature evaporate under a stream of nitrogen to give N-(4-methoxyphenyl)-N'-ethylidene hydrazine.

Aufarbeitung

  1. dry with materialDry the organic layer over MgSO4
  2. filtrationfilter
  3. customevaporate in vacuo
  4. customto give a residue
  5. additionWhen the addition
  6. temperaturewarm to ambient temperature
  7. customAfter 1 hour at ambient temperature evaporate under a stream of nitrogen

Quellen und Nachweise

ORD-Eintrag
ord-6c909d6da00b43a8ab6e2cf5c88b3b74
Quelldatensatz
uspto-grants-1999_03
Patentnummer
US05877202

Notizen zur Reaktion

Wird geladen…