HCID 86752382, Verbindung → HCID 86752383, Verbindung
Reaktionsgleichung
[OH:1][CH2:2][C:3]1[CH:17]=[CH:16][C:6]([O:7][CH2:8][CH2:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[C:5]([N+:18]([O-:20])=[O:19])[CH:4]=1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>>[CH:2]([C:3]1[CH:17]=[CH:16][C:6]([O:7][CH2:8][CH2:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[C:5]([N+:18]([O-:20])=[O:19])[CH:4]=1)=[O:1]Komponenten
3
Versuchsvorschrift
4-[4-(Hydroxymethyl)2-nitrophenoxy]butanoic acid, ethyl ester (300 mg, 1.06 mmol) is treated with 799 mg (3.71 mmol) of pyridinium chlorochromate by the procedure described in Example 5 to give 188 mg (63%) of 4-(4-formyl-2-nitrophenoxy)butanoic acid, ethyl ester as a colorless oil. The 1H NMR (300 MHz, CDCl3) is consistent with the desired product; IR (neat) 1730, 1700, 1610, 1570 cm-1 ; MS (CI) m/e 282 (M+H).
Quellen und Nachweise
- ORD-Eintrag
- ord-23d288ac5e4940c9ab75dcfc2a57839a
- Quelldatensatz
- uspto-grants-1999_03
- DOI