2-(4-Aminophenoxy)acetamide → HCID 70187532, Verbindung
Reaktionsgleichung
Cl[C:2]1[CH:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[CH:10]=2)[N:5]=[CH:4][N:3]=1.[C:16]([CH2:19][O:20][C:21]1[CH:27]=[CH:26][C:24]([NH2:25])=[CH:23][CH:22]=1)(=[O:18])[NH2:17]>>[C:16]([CH2:19][O:20][C:21]1[CH:27]=[CH:26][C:24]([NH:25][C:2]2[CH:7]=[C:6]([NH:8][C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[CH:10]=3)[N:5]=[CH:4][N:3]=2)=[CH:23][CH:22]=1)(=[O:18])[NH2:17]Komponenten
3
Versuchsvorschrift
Using an analogous procedure to that described in Example 13, 4-chloro-6-(3'-methylanilino)pyrimidine (0.23 g) was reacted with 4-(carbamoylmethoxy)aniline to give 4-[4'-(carbamoylmethoxy)anilino]6-(3'-methylanilino)pyrimidine in 30% yield, m.p. 212°-215° C.;
Quellen und Nachweise
- ORD-Eintrag
- ord-d47c389894e440869ef064115a3a2fa9
- Quelldatensatz
- uspto-grants-1999_03