3-Methoxyphenyl isocyanate → N-(2-hydroxy-4-nitrophenyl)-N'-(3-methoxyphenyl)urea

HRID 1419357Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1419357
[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([N:20]=[C:21]=[O:22])[CH:17]=[CH:18][CH:19]=1>>[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH:4][C:21]([NH:20][C:16]1[CH:17]=[CH:18][CH:19]=[C:14]([O:13][CH3:12])[CH:15]=1)=[O:22]

Komponenten

3

Edukt 2

HCID 878433-Methoxyphenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

Produkt 1

HCID 21184674N-(2-hydroxy-4-nitrophenyl)-N'-(3-methoxyphenyl)ureaAusbeute 46,2 %

Versuchsvorschrift

N-(2-Hydroxy-4-nitrophenyl)-N'-(3-methoxyphenyl)urea was prepared from 2-hydroxy 4-nitro aniline (154 mg, 1.0 mmol) and 3-methoxy phenyl isocyanate(1.0 mmol) according to the procedure in General Method B. The product was purified by dilution with methylene chloride and precipitation with hexanes. Filtering afforded the title compound (140 mg, 46%). EI-MS m/z 302(M-H)-

Aufarbeitung

  1. customThe product was purified by dilution with methylene chloride and precipitation with hexanes
  2. filtrationFiltering

Quellen und Nachweise

ORD-Eintrag
ord-d0f4bdd00bc24dfaa35a8c2b0121b294
Quelldatensatz
uspto-grants-1999_03
Patentnummer
US05886044

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