Thionyl Chloride → HCID 22625098, Verbindung
Reaktionsgleichung
S(Cl)([Cl:3])=O.O[CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=1>ClC(Cl)Cl>[ClH:3].[Cl:3][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 5 °C
Versuchsvorschrift
Thionyl chloride (2.2 ml, 30 mmol) was added slowly to a solution of 4-(3-hydroxypropoxy)pyridine (3.1 g, 20 mmol) in trichloromethane (40 ml) at 5° C. The mixture was stirred at 5° C. for 1 hour and then at ambient temperature for 2 hours. The volatiles were removed by evaporation, the residue azeotroped with toluene and dried under vacuum to give 4-(3-chloropropoxy)pyridine hydrochloride (3.81 g, 91%) as a solid.
Aufarbeitung
- waitat ambient temperature for 2 hours
- customThe volatiles were removed by evaporation
- customthe residue azeotroped with toluene
- customdried under vacuum
Quellen und Nachweise
- ORD-Eintrag
- ord-1eeb466e9f244f95a2cb5c33e25cec24
- Quelldatensatz
- uspto-grants-2000_06
- Patentnummer
- US06071921
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