HCID 58189029, Verbindung → HCID 178491991, Verbindung
Reaktionsgleichung
[CH2:1]([C@@H:8]1[NH:13][CH2:12][CH2:11][N:10]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[C:16]([O:22][CH:23]([CH3:25])[CH3:24])[CH:15]=2)[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([O:28][C:29](=O)[CH2:30][C:31]1[NH:35][CH:34]=[N:33][N:32]=1)C>>[CH2:1]([C@H:8]1[CH2:9][N:10]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[C:16]([O:22][CH:23]([CH3:25])[CH3:24])[CH:15]=2)[CH2:11][CH2:12][N:13]1[C:29](=[O:28])[CH2:30][C:31]1[NH:35][CH:34]=[N:33][N:32]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Komponenten
3
Versuchsvorschrift
Prepared using the same procedure described in Example 275 from (S)-3-benzyl-1-(3-isopropoxy-4-methoxy-phenyl)-piperazine and (4H-[1,2,4]triazol-3-yl)-acetic acid ethyl ester with heating for 5 days to afford the title compound as a yellow solid (94 mg, 25%). LC/MS (Method B) 3.12 min, [M+1]+ 450.
Aufarbeitung
- customPrepared
- temperaturewith heating for 5 days