HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ammonium formate → Ethyl 2-(4-aminophenyl)-1,3-thiazole-5-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ammonium formate | HCID 2723923 | — |
| Edukt | Ethyl 2-(4-nitrophenyl)-1,3-thiazole-5-carboxylate | HCID 53403660 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | Ethyl 2-(4-aminophenyl)-1,3-thiazole-5-carboxylate | HCID 67548762 | 75% |
Reaktionsschritte
The same operation as in Example (90d) was performed using ethyl 2-(4-nitrophenyl)-1,3-thiazole-5-carboxylate obtained in Example (91a) (0.18 g, 0.65 mmol), 10% Pd/C (wet, 0.1 g), ammonium formate (0.2 g, 3.24 mmol) and methanol (5 mL), to obtain 0.12 g of the crude title compound as a yellow solid (75%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08927588B2 |
| Quelldatensatz | uspto-grants-2015_01 |
| ORD ID | ord-db93412fd98f432ba9775bef29310d21 |
| Quellennotiz | uspto-grants-2015_01 |