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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1425033Erstellt: 27. Oktober 2026

Ammonium formate → Ethyl 2-(4-aminophenyl)-1,3-thiazole-5-carboxylate

https://huagongshe.com/reaction/1425033

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktAmmonium formateHCID 2723923—
EduktEthyl 2-(4-nitrophenyl)-1,3-thiazole-5-carboxylateHCID 53403660—
KatalysatorPalladiumHCID 23938—
LösungsmittelMethanolHCID 887—
ProduktEthyl 2-(4-aminophenyl)-1,3-thiazole-5-carboxylateHCID 6754876275%

Reaktionsschritte

The same operation as in Example (90d) was performed using ethyl 2-(4-nitrophenyl)-1,3-thiazole-5-carboxylate obtained in Example (91a) (0.18 g, 0.65 mmol), 10% Pd/C (wet, 0.1 g), ammonium formate (0.2 g, 3.24 mmol) and methanol (5 mL), to obtain 0.12 g of the crude title compound as a yellow solid (75%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08927588B2
Quelldatensatzuspto-grants-2015_01
ORD IDord-db93412fd98f432ba9775bef29310d21
Quellennotizuspto-grants-2015_01