2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborate → HCID 87286286, Verbindung
Reaktionsgleichung
[C:1]([O:5][C:6]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([NH:24][C:25]1[CH:33]=[CH:32][C:28]([C:29]([OH:31])=[O:30])=[CH:27][CH:26]=1)=[O:23])=[O:7])([CH3:4])([CH3:3])[CH3:2].[B-](F)(F)(F)F.CN(C(O[N:47]1[C:52](=[O:53])[CH2:51][CH2:50][C:48]1=[O:49])=[N+](C)C)C>>[O:49]=[C:48]1[CH2:50][CH2:51][C:52](=[O:53])[N:47]1[O:30][C:29](=[O:31])[C:28]1[CH:27]=[CH:26][C:25]([NH:24][C:22](=[O:23])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:7])=[CH:33][CH:32]=1Komponenten
3
Versuchsvorschrift
4-(15-tert-Butoxycarbonylpentadecanoylamino)-benzoic acid (29 mg, 0.063 mmol) was converted to the succinimidyl ester using TSTU similar to described above.
Quellen und Nachweise
- ORD-Eintrag
- ord-303a7620cd9c4d3ca0bfc39ff4f0e798
- Quelldatensatz
- uspto-grants-2015_01