5,6,7,8-Tetrahydro-2-naphthylamine → 1-(1-oxo-1,2,7,8,9,10-hexahydro-benzo[f]quinazolin-3-yl)-1H-pyrazole-4-carboxylic acid ethyl ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	5,6,7,8-Tetrahydro-2-naphthylamine	HCID 75193	—
Edukt	1-(4-oxo-3,4,6,7,8,9-hexahydro-benzo[g]quinazolin-2-yl)-1H-pyrazole-4-carboxylic acid ethyl ester	HCID 136337181	—
Produkt	1-(1-oxo-1,2,7,8,9,10-hexahydro-benzo[f]quinazolin-3-yl)-1H-pyrazole-4-carboxylic acid ethyl ester	HCID 136337182	—

Reaktionsschritte

The titled compound was prepared in a manner analogous to Example 131, steps A-B, using 5,6,7,8-tetrahydro-naphthalen-2-ylamine in step A. Step B yielded a 2:1 mixture of 1-(4-oxo-3,4,6,7,8,9-hexahydro-benzo[g]quinazolin-2-yl)-1H-pyrazole-4-carboxylic acid ethyl ester and the titled compound.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08937078B2
Quelldatensatz	uspto-grants-2015_01
ORD ID	ord-06b0dac4f44646938b8643ded06d85c2
Quellennotiz	uspto-grants-2015_01