HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl iodide → 1-Trityl-4-methoxymethylpyrazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl iodide | HCID 6328 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | (1-Trityl-1H-pyrazol-4-yl)methanol | HCID 10688521 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 1-Trityl-4-methoxymethylpyrazole | HCID 68530902 | 93% |
Reaktionsschritte
This compound is obtained by reacting 1-trityl-4-hydroxymethylpyrazole (555 mg; 1.63 mmol) in dry tetrahydrofuran with sodium hydride (98 mg; 2.44 mmol) and iodomethane (0.5 mL; 8.15 mmol). Yield: 93% (536 mg, 1.51 mmol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08940273B2 |
| Quelldatensatz | uspto-grants-2015_01 |
| ORD ID | ord-6641dc0a1dd34e46b0fd2afdbabbbfbe |
| Quellennotiz | uspto-grants-2015_01 |