Mupirocin → ZE7Qpy4258
Reaktionsgleichung
CC1(C)S[C@@H:5]2[C@H:7]([NH:10][C:11]([C@H:13](N)[C:14]3[CH:15]=[CH:16][C:17](O)=[CH:18][CH:19]=3)=O)[C:8](=O)N2[C@H]1C(O)=O.[CH2:26]1C(=O)[N:28]2[C@@H](C([O-])=O)/C(/O[C@H:27]12)=C/CO.[K+].C[C@@H:42]([C@@H](O)C)[C@@H:43]1O[C@H:44]1[CH2:46][C@@H:47]1[C@@H](O)[C@@H:51](O)[C@H:50]([CH2:55]/[C:56](/[CH3:72])=C/C(OCCCCCCCCC(O)=O)=O)[O:49][CH2:48]1.[CH:76]1C(NC(NC(NCCCCCCNC(NC(NC2C=CC(Cl)=CC=2)=N)=N)=N)=N)=CC=C(Cl)[CH:77]=1.C(O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O>>[CH3:26][C:27]1[C:5]2[CH2:76][CH2:77][N:10]([CH2:11][CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:7]=2[C:8]2[CH:51]=[C:50]([O:49][C:48]3[CH:42]=[CH:43][CH:44]=[CH:46][CH:47]=3)[CH:55]=[CH:56][C:72]=2[N:28]=1Komponenten
4
Versuchsvorschrift
Co-amoxiclav (1000/200 mg infusion, GlaxoSmithKline) was purchased from St George's NHS Hospital, London. Mupirocin was purchased from Sigma Aldrich Ltd (Poole, Dorset, UK). Chlorhexidine gluconate was purchased from Sigma Aldrich Ltd (Poole, Dorset, UK). 4-methyl-8-phenoxy-1-(2-phenylethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]quinoline (in hydrochloride salt form) was provided by Helperby Therapeutics.