Methyl 3-(chlorosulfonyl)propanoate → Methyl 3-(4-(2-(1-(5-methylpyrazin-2-yl)piperidin-4-yloxy)benzo[d]thiazol-6-yl)-5,6-dihydropyridin-1(2H)-ylsulfonyl)propanoate
Reaktionsgleichung
[CH3:1][C:2]1[N:3]=[CH:4][C:5]([N:8]2[CH2:13][CH2:12][CH:11]([O:14][C:15]3[S:16][C:17]4[CH:23]=[C:22]([C:24]5[CH2:25][CH2:26][NH:27][CH2:28][CH:29]=5)[CH:21]=[CH:20][C:18]=4[N:19]=3)[CH2:10][CH2:9]2)=[N:6][CH:7]=1.Cl[S:31]([CH2:34][CH2:35][C:36]([O:38][CH3:39])=[O:37])(=[O:33])=[O:32]>>[CH3:1][C:2]1[N:3]=[CH:4][C:5]([N:8]2[CH2:13][CH2:12][CH:11]([O:14][C:15]3[S:16][C:17]4[CH:23]=[C:22]([C:24]5[CH2:25][CH2:26][N:27]([S:31]([CH2:34][CH2:35][C:36]([O:38][CH3:39])=[O:37])(=[O:33])=[O:32])[CH2:28][CH:29]=5)[CH:21]=[CH:20][C:18]=4[N:19]=3)[CH2:10][CH2:9]2)=[N:6][CH:7]=1Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
Compound 50D was prepared from Compound 50C and methyl 3-(chlorosulfonyl)propanoate in a similar manner to the procedure described for Compound Example 16.
Quellen und Nachweise
- ORD-Eintrag