HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Iodine chloride → 3-Chloro-4-amino-5-iodobenzylamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Iodine chloride | HCID 24640 | — |
| Edukt | 4-(Aminomethyl)-2-chloroaniline | HCID 21880650 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 3-Chloro-4-amino-5-iodobenzylamine | HCID 58962991 | 42% |
Reaktionsschritte
To 3-Chloro-4-aminobenzylamine (200 mg, 1.28 mmol) in methanol (5 mL) was added iodine monochloride (230 mg, 1.42 mmol). The mixture was stirred for 1 hour, then purified by HPLC to give 3-chloro-4-amino-5-iodobenzylamine (150 mg, 42%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07612069B2 |
| Quelldatensatz | uspto-grants-2009_11 |
| ORD ID | ord-eede25dc32984281a7c2effb36f4b59a |
| Quellennotiz | uspto-grants-2009_11 |