4-Fluorobenzaldehyde → N-(2-{2-[(4-Fluoro-phenyl)-(4-hydroxy-5-isopropyl-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)-methyl]-1H-indol-3-yl}-ethyl)-acetamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-Fluorobenzaldehyde	HCID 68023	—
Edukt	N-Acetyltryptamine	HCID 70547	—
Edukt	4-Hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one	HCID 56604111	—
Produkt	N-(2-{2-[(4-Fluoro-phenyl)-(4-hydroxy-5-isopropyl-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)-methyl]-1H-indol-3-yl}-ethyl)-acetamide	HCID 57933472	—

Reaktionsschritte

Using general procedure C, 4-hydroxy-5-isopropyl-1,5-dihydro-pyrrol-2-one (Lit. 11) was reacted with 4-fluoro-benzaldehyde and N-[2-(1H-indol-3-yl)-ethyl]-acetamide to give the title compound as a yellow solid. MS: 450.3 ([M+H]+).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07612099B2
Quelldatensatz	uspto-grants-2009_11
ORD ID	ord-e2e8a92d5d8a41ee89a1491bf99577e9
Quellennotiz	uspto-grants-2009_11