7-Methoxy-2-tetralone → 6-Methoxy-3-(4-methoxy-2-nitrophenyl)-1,2-dihydronaphthalene

HRID 1433863Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1433863
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH2:7][CH2:8][C:9](=O)[CH2:10]2)=[CH:5][CH:4]=1.FC(F)(F)S(OC1CCC2C(=CC(OC)=CC=2)C=1)(=O)=O.C([Sn](CCCC)(CCCC)[C:39]1[CH:44]=[CH:43][C:42]([O:45][CH3:46])=[CH:41][C:40]=1[N+:47]([O-:49])=[O:48])CCC>>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6](=[CH:5][CH:4]=1)[CH2:7][CH2:8][C:9]([C:39]1[CH:44]=[CH:43][C:42]([O:45][CH3:46])=[CH:41][C:40]=1[N+:47]([O-:49])=[O:48])=[CH:10]2

Komponenten

4

Edukt 3

HCID 777857-Methoxy-2-tetraloneHCID 230874467-Methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonateHCID 23087474Tributyl(4-methoxy-2-nitrophenyl)tin

Produkt 1

HCID 230875356-Methoxy-3-(4-methoxy-2-nitrophenyl)-1,2-dihydronaphthalene

Versuchsvorschrift

Synthesized from 7-methoxy-2-tetralone according to an analogous synthetic method to Preparation Example 82 described above, 7-methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate (3.5 g) and tributyl(4-methoxy-2-nitrophenyl)tin (18 g) were used according to an analogous synthetic method to Preparation Example 77 to provide the title compound (1.9 g).

Aufarbeitung

  1. customwere used according to an analogous synthetic method to Preparation Example 77

Quellen und Nachweise

ORD-Eintrag
ord-aec3a4cc0fa34e72aa5bd13c7fcc48b3
Quelldatensatz
uspto-grants-2009_11
Patentnummer
US07612114B2

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