4-(2-Azepan-1-ylethoxy)benzoic acid hydrochloride → HCID 66626648, Verbindung
Reaktionsgleichung
[CH2:1]([NH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH:10]1[CH2:19][CH2:18][C:17]2[C:12](=[CH:13][CH:14]=[C:15]([O:20]C)[CH:16]=2)[CH2:11]1)[CH3:2].Cl.[N:23]1([CH2:30][CH2:31][O:32][C:33]2[CH:41]=[CH:40][C:36]([C:37](O)=O)=[CH:35][CH:34]=2)[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1.N1(CCOC2C=CC(CN(CC)C3C=CC=CC=3C3CCC4C(=CC=C(OC)C=4)C3)=CC=2)CCCCCC1>>[N:23]1([CH2:30][CH2:31][O:32][C:33]2[CH:41]=[CH:40][C:36]([CH2:37][CH2:2][CH2:1][NH:3][C:4]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=3[CH:10]3[CH2:19][CH2:18][C:17]4[CH:16]=[C:15]([OH:20])[CH:14]=[CH:13][C:12]=4[CH2:11]3)=[CH:35][CH:34]=2)[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1Komponenten
4
Versuchsvorschrift
Synthesized from ethyl[2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine and 4-(2-azepan-1-ylethoxy)benzoic acid hydrochloride according to an analogous synthetic method to Example 152, [4-(2-azepan-1-ylethoxy)benzyl]ethyl[2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine (504 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (394 mg).