4-Amino-2,2,6,6-tetramethylpiperidine → 1-{5'-[5-Methyl-2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-[2,2']bithiophenyl-5-yl}-ethanone

HRID 1434956

Reaktionsgleichung

Reaktionsgleichung von HRID 1434956
[S:1]1[C:5]([C:6](=[O:8])[CH3:7])=[CH:4][CH:3]=[C:2]1[C:9]1[S:10][CH:11]=[CH:12][CH:13]=1.Cl[C:15]1[N:20]=[C:19](Cl)[C:18]([CH3:22])=[CH:17][N:16]=1.[NH2:23][CH:24]1[CH2:29][C:28]([CH3:31])([CH3:30])[NH:27][C:26]([CH3:33])([CH3:32])[CH2:25]1>>[CH3:22][C:18]1[C:17]([C:11]2[S:10][C:9]([C:2]3[S:1][C:5]([C:6](=[O:8])[CH3:7])=[CH:4][CH:3]=3)=[CH:13][CH:12]=2)=[N:16][C:15]([NH:23][CH:24]2[CH2:25][C:26]([CH3:33])([CH3:32])[NH:27][C:28]([CH3:31])([CH3:30])[CH2:29]2)=[N:20][CH:19]=1

Komponenten

4

Edukt 3

HCID 375244-Amino-2,2,6,6-tetramethylpiperidineHCID 74508Pyrimidine, 2,4-dichloro-5-methyl-HCID 6064225-Acetyl-2,2'-bithienyl

Produkt 1

HCID 113055801-{5'-[5-Methyl-2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-[2,2']bithiophenyl-5-yl}-ethanone

Versuchsvorschrift

The title compound was prepared analogous to Method A, starting from 1-[2,2′]bithiophenyl-5-yl-ethanone, 2,4-dichloro-5-methyl-pyrimidine and 4-amino-2,2,6,6-tetramethylpiperidine.

Quellen und Nachweise

ORD-Eintrag
ord-68f7aa3afb2e462382d46eee149c1bb2
Quelldatensatz
uspto-grants-2009_11
Patentnummer
US07615562B2

Verknüpfte Notizen

Wird geladen…