1-Benzothiophene-3-sulfonyl chloride → [4-Amino-2-[1-(benzo[b]thiophene-3-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-Benzothiophene-3-sulfonyl chloride	HCID 2776340	—
Edukt	[4-Amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone	HCID 9997668	—
Produkt	[4-Amino-2-[1-(benzo[b]thiophene-3-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone	HCID 21070416	—

Reaktionsschritte

The title compound was prepared from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone, Example 59, and benzo[b]thiophene-3-sulfonyl chloride (Maybridge) by the procedure described in Example 152. HR-MS (ES, m/z) calculated for C25H25FN5O4S2 [(M+H)+] 542.1327, observed 542.1331.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07615634B2
Quelldatensatz	uspto-grants-2009_11
ORD ID	ord-eb96601d6ccd4dc2a7f617c743ccb42d
Quellennotiz	uspto-grants-2009_11