Trifluoroacetic acid → HCID 86615824, Verbindung
Reaktionsgleichung
C(OC([N:8]1[CH2:12][CH2:11][C@H:10]([C:13]([OH:15])=[O:14])[CH2:9]1)=O)(C)(C)C.[C:16]([OH:22])([C:18]([F:21])([F:20])[F:19])=[O:17]>>[F:19][C:18]([F:21])([F:20])[C:16]([O-:22])=[O:17].[C:13]([C@H:10]1[CH2:11][CH2:12][NH2+:8][CH2:9]1)([OH:15])=[O:14]Komponenten
3
Versuchsvorschrift
(3S)-1-(tert-Butoxycarbonyl)pyrrolidine-3-carboxylic acid (0.5 g, 2.34 mmol) was stirred in TFA (20 mL) for 3 h. The solvent was removed to provide the title compound as yellow oil that was used for the next step without further purification. Yield: 0.50 g (99%).
Aufarbeitung
- customThe solvent was removed
Quellen und Nachweise
- ORD-Eintrag
- ord-bbaa2d0b92574a77bf6169f662ad3092
- Quelldatensatz
- uspto-grants-2009_11
- Patentnummer
- US07615642B2
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