HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl {2-[({5-[2-(methylsulfanyl)-4-pyrimidinyl]-2-thienyl}sulfonyl)amino]-1,3-thiazol-4-yl}acetate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Thiazoleacetic acid, 2-amino-, ethyl ester | HCID 104454 | — |
| Edukt | 5-(2-(Methylthio)-4-pyrimidinyl)-2-thiophenesulfonyl chloride | HCID 2736995 | — |
| Produkt | Ethyl {2-[({5-[2-(methylsulfanyl)-4-pyrimidinyl]-2-thienyl}sulfonyl)amino]-1,3-thiazol-4-yl}acetate | HCID 10115258 | — |
Reaktionsschritte
The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 5-[2-(methylthio)pyrimidin-4-yl]thiophene-2-sulfonyl chloride as described in the synthetic METHOD B to give a white solid (34.5 mg) with purity >90%. MS (pos) m/z 475.3.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07618961B2 |
| Quelldatensatz | uspto-grants-2009_11 |
| ORD ID | ord-750e8d3bccc5492d973356b02e800870 |
| Quellennotiz | uspto-grants-2009_11 |