HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl (2-{[(4-bromo-2,5-difluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Thiazoleacetic acid, 2-amino-, ethyl ester | HCID 104454 | — |
| Edukt | 4-Bromo-2,5-difluorobenzenesulfonyl Chloride | HCID 574590 | — |
| Produkt | Ethyl (2-{[(4-bromo-2,5-difluorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate | HCID 10275050 | — |
Reaktionsschritte
The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 4-bromo-2,5-difluorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (21.9 mg) with purity >90%. MS (pos) m/z 441.0, 443.0.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07618961B2 |
| Quelldatensatz | uspto-grants-2009_11 |
| ORD ID | ord-15fe492acbe34b05979d10fa7f3cc722 |
| Quellennotiz | uspto-grants-2009_11 |