2-Ethenyl-5-nitropyridine → 6-Ethylpyridin-3-amine

HRID 1437216Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1437216
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([CH:10]=[CH2:11])=[N:8][CH:9]=1)([O-])=O.[H][H]>C(O)C.[C].[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([CH2:10][CH3:11])=[N:8][CH:9]=1

Komponenten

5

Edukt 2

HCID 230905502-Ethenyl-5-nitropyridineHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 138607296-Ethylpyridin-3-amine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

10% Palladium-carbon (50% wet, 90 mg) was added to 5-nitro-2-vinylpyridine (450 mg) in ethanol (30 mL), followed by stirring in a hydrogen atmosphere at room temperature for 15 hours. The catalyst was removed from the reaction mixture by filtration. Subsequently, the solvent was evaporated under reduced pressure, to thereby give the title compound as an oily substance (359 mg, 98%).

Aufarbeitung

  1. customThe catalyst was removed from the reaction mixture by filtration
  2. customSubsequently, the solvent was evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-a416115830cf4a28b2528ea5ae593b4e
Quelldatensatz
uspto-grants-2009_11
Patentnummer
US07622471B2

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