Methylamine → N-methylpiperidine-2-carboxamide
Reaktionsgleichung
C(O[N:9]1[CH2:14][CH2:13][CH2:12][CH2:11][CH:10]1[C:15]([OH:17])=O)C1C=CC=CC=1.[CH3:18][NH2:19]>O1CCCC1>[CH3:18][NH:19][C:15]([CH:10]1[CH2:11][CH2:12][CH2:13][CH2:14][NH:9]1)=[O:17]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The general procedure of Referential Example 131 was repeated through use of N-benzyloxypiperidine-2-carboxylic acid (2.0 g) and 1.0 M methylamine in tetrahydrofuran (4 mL), to thereby give the title compound as an oily product (970 mg, quantitative amount).
Quellen und Nachweise
- ORD-Eintrag
- ord-e7d34bec75684832a71b0a225f0e3b6c
- Quelldatensatz
- uspto-grants-2009_11
- Patentnummer
- US07622471B2
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