Pyrrolidine → [5-(3-Piperidin-1-yl-propoxy)-1H-pyrrolo[2,3-b]pyridin-2-yl]-pyrrolidin-1-yl-methanone
Reaktionsgleichung
Cl.[N:2]1([CH2:8][CH2:9][CH2:10][O:11][C:12]2[CH:13]=[C:14]3[CH:20]=[C:19]([C:21]([OH:23])=O)[NH:18][C:15]3=[N:16][CH:17]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[NH:24]1[CH2:28][CH2:27][CH2:26][CH2:25]1>>[N:2]1([CH2:8][CH2:9][CH2:10][O:11][C:12]2[CH:13]=[C:14]3[CH:20]=[C:19]([C:21]([N:24]4[CH2:28][CH2:27][CH2:26][CH2:25]4)=[O:23])[NH:18][C:15]3=[N:16][CH:17]=2)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1Komponenten
3
Versuchsvorschrift
The title compound was synthesized in analogy to example 1 from 5-(3-piperidin-1-yl-propoxy)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid hydrochloride and pyrrolidine to give the desired product as a colorless solid (70%).
Quellen und Nachweise
- ORD-Eintrag
- ord-be0def503c3a4418a1bd541b0a575ce6
- Quelldatensatz