Chloroacetonitrile → HCID 20393696, Verbindung

HRID 1439213Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1439213
[C:1]([C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[C:11]([Cl:16])[C:10]=1[Cl:17])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:19][C:20]#[N:21].C([O-])([O-])=O.[K+].[K+]>CC(C)=O>[C:1]([C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:19][C:20]#[N:21])=[C:11]([Cl:16])[C:10]=1[Cl:17])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

5

Edukt 3

HCID 7856ChloroacetonitrileHCID 11430Potassium CarbonateHCID 14009997(2,3-Dichloro-4-hydroxyphenyl)(phenyl)methanone

Produkt 1

HCID 20393696HCID 20393696, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

A mixture of 26.70 g. (0.10 mole) of 4-benzoyl-2,3-dichlorophenol, 7.40 g. (0.10 mole) of chloroaceto nitrile, 10.40 g. (0.15 mole) of anhydrous K2CO3 and catalytic amount of KI in 200 ml. of acetone was refluxed overnight. The residue was triturated with ether and the product was collected by filtration and dried to yield 22.80 g. (75%); m.p. 110°-112°. This product was used in the next step without further purification.

Aufarbeitung

  1. additionA mixture of 26.70 g
  2. customThe residue was triturated with ether
  3. filtrationthe product was collected by filtration
  4. customdried
  5. customto yield 22.80 g
  6. customThis product was used in the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-a6cb90a5f50c4dedba1a89701683a8a0
Quelldatensatz
uspto-grants-1977_11
Patentnummer
US04058559

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