Benzyl 7-{2-(3-benzyloxy-4-[4-fluorophenoxy]butyl)-1,1,4-trioxo-3-thiazolidinyl}heptanoate → 7-[2-(3-Hydroxy-4-propoxybutyl)-4-oxo-3-thiazolidinyl]heptanoic Acid
Reaktionsgleichung
C([O:8][CH:9]([CH2:36][O:37][C:38]1C=CC(F)=[CH:40][CH:39]=1)[CH2:10][CH2:11][CH:12]1[N:16]([CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([O:25]CC2C=CC=CC=2)=[O:24])[C:15](=[O:33])[CH2:14][S:13]1(=O)=O)C1C=CC=CC=1.C(OC(COCCC)CCC1N(CCCCCCC(OCC2C=CC=CC=2)=O)C(=O)CS1)C1C=CC=CC=1>>[OH:8][CH:9]([CH2:36][O:37][CH2:38][CH2:39][CH3:40])[CH2:10][CH2:11][CH:12]1[N:16]([CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24])[C:15](=[O:33])[CH2:14][S:13]1Komponenten
3
Versuchsvorschrift
This compound is prepared essentially by the method described in Example 5, Step E, except that the benzyl 7-{2-[3-benzyloxy-4-(4-fluorophenoxy)butyl]-1,1,4-trioxo-3-thiazolidinyl}heptanoate is replaced by benzyl 7-[2-(3-benzyloxy-4-propoxybutyl)-4-oxo-3-thiazolidinyl]heptanoate. This method provides the title compound as a viscous, pale yellow oil.