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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1442523Erstellt: 26. Oktober 2026

2,3,5-Trifluorobenzaldehyde → 2-[Bis(cyclopropylmethyl)amino]-3,5-difluorobenzaldehyde

https://huagongshe.com/reaction/1442523

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2,3,5-TrifluorobenzaldehydeHCID 2776950—
EduktBis(cyclopropylmethyl)amineHCID 15284719—
EduktN-(cyclopentylmethyl)-N-ethylamineHCID 43163716—
Produkt2-[Bis(cyclopropylmethyl)amino]-3,5-difluorobenzaldehydeHCID 86628977—

Reaktionsschritte

By using 2,3,5-trifluorobenzaldehyde instead of 2-fluoro-5-(trifluoromethyl)benzaldehyde, and N,N-bis(cyclopropylmethyl)amine synthesized by the method described in International Patent Publication WO2006/073973 instead of N-(cyclopentylmethyl)-N-ethylamine, reactions and treatments were performed in the same manner as those of Step 3 of Example 1 to obtain 2-[bis(cyclopropylmethyl)amino]-3,5-difluorobenzaldehyde as a yellow oil.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07659271B2
Quelldatensatzuspto-grants-2010_02
ORD IDord-1c44551e5365410ba8aadd71b3bf484e
Quellennotizuspto-grants-2010_02