HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Aminocinnamic acid ethyl ester → 3-(3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-acrylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Aminocinnamic acid ethyl ester | HCID 97825 | — |
| Edukt | 5-(3-Chlorophenyl)furan-2-carboxylic acid | HCID 736256 | — |
| Produkt | 3-(3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-acrylic acid ethyl ester | HCID 68490796 | — |
Reaktionsschritte
Carboxylic acid (65) (58 mg, 0.26 mmol) was coupled to ethyl ester (60) (50 mg, 0.26 mmol) using Method C. The crude residue was purified by column chromatography eluting with a stepped gradient of 10-15% EtOAc in heptane to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07662839B2 |
| Quelldatensatz | uspto-grants-2010_02 |
| ORD ID | ord-57635100a5f04ce58e90eeb35e11ad1a |
| Quellennotiz | uspto-grants-2010_02 |