HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Aminocinnamic acid ethyl ester → 3-(3-{[5-(4-Fluoro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-acrylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Aminocinnamic acid ethyl ester | HCID 97825 | — |
| Edukt | 5-(4-Fluorophenyl)furan-2-carboxylic acid | HCID 738991 | — |
| Produkt | 3-(3-{[5-(4-Fluoro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-acrylic acid ethyl ester | HCID 68497349 | — |
Reaktionsschritte
5-(4-Fluoro-phenyl)-furan-2-carboxylic acid (54 mg, 0.26 mmol) was coupled to ethyl ester (60) (50 mg, 0.26 mmol) using Method C. The crude residue was purified by column chromatography eluting with 10% EtOAc in heptane to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07662839B2 |
| Quelldatensatz | uspto-grants-2010_02 |
| ORD ID | ord-2d93fd4667ee45978646eacc26cc38ce |
| Quellennotiz | uspto-grants-2010_02 |