2-Nitrobenzyl chloride → 2-[(2-nitrophenyl)methyl]isoindole-1,3-dione

HRID 1447400

Reaktionsgleichung

Reaktionsgleichung von HRID 1447400
[CH:1]1[CH:6]=[C:5]2[C:7]([N-:9][C:10](=[O:11])[C:4]2=[CH:3][CH:2]=1)=[O:8].[K+].[N+:13]([C:16]1[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18]Cl)([O-:15])=[O:14]>CN(C)C=O>[N+:13]([C:16]1[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18][N:9]1[C:7](=[O:8])[C:5]2=[CH:6][CH:1]=[CH:2][CH:3]=[C:4]2[C:10]1=[O:11])([O-:15])=[O:14]

Komponenten

4

Edukt 2

HCID 119212-Nitrobenzyl chlorideHCID 3356745Potassium phthalimide

Produkt 1

HCID 3195372-[(2-nitrophenyl)methyl]isoindole-1,3-dione

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

The starting material is prepared as follows: The mixture of 54.0 of N-potassium phthalimide, 50.0 g of o-nitrobenzyl chloride and 120 ml of dimethylformamide is refluxed for 3 hours and poured into 900 ml of ice-water while stirring. After 30 minutes, it is filtered, and the residue washed with water, to yield the N-o-nitrobenzyl-phthalimide melting at 190-209°.

Aufarbeitung

  1. customThe starting material is prepared
  2. temperatureis refluxed for 3 hours
  3. filtrationit is filtered
  4. washthe residue washed with water

Quellen und Nachweise

ORD-Eintrag
ord-681934bce20d45c28e36421d9404cb55
Quelldatensatz
uspto-grants-1982_02
Patentnummer
US04316900

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