Potassium Hydroxide → 1-(1,3,4-Thiadiazol-2-yl)piperazine
Reaktionsgleichung
[OH-].[K+].[CH:3]([N:5]1[CH2:10][CH2:9][NH:8][CH2:7][CH2:6]1)=O.Br[C:12]1[S:13]C=[N:15][N:16]=1>>[S:13]1[CH:12]=[N:16][N:15]=[C:3]1[N:5]1[CH2:10][CH2:9][NH:8][CH2:7][CH2:6]1Komponenten
4
Versuchsvorschrift
The starting 1-(1,3,4-thiadiazol-2-yl)-piperazine was prepared by hydrolyzing with alcoholic potassium hydroxide the crude formyl derivative, itself prepared by condensing 1-formyl piperazine with 2-bromo-1,3,4-thiadiazole melting at 74° C. (Goerdeler and al., Ber 89 1534 (1956)).
Quellen und Nachweise
- ORD-Eintrag
- ord-9e58822d7c0d4b0191de488e537d79db
- Quelldatensatz
- uspto-grants-1979_12
- Patentnummer
- US04177272
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