Sodium Bicarbonate → Propyl N-((5-methyl-2-(isopropyl)cyclohexyl)carbonyl)glycinate
Reaktionsgleichung
[CH:1]1([CH3:13])[CH2:6][CH2:5][CH:4]([CH:7]([CH3:9])[CH3:8])[CH:3]([C:10](Cl)=[O:11])[CH2:2]1.Cl.[CH2:15]([O:18][C:19](=[O:22])[CH2:20][NH2:21])[CH2:16][CH3:17].C(=O)(O)[O-].[Na+]>>[CH2:15]([O:18][C:19](=[O:22])[CH2:20][NH:21][C:10]([CH:3]1[CH:4]([CH:7]([CH3:9])[CH3:8])[CH2:5][CH2:6][CH:1]([CH3:13])[CH2:2]1)=[O:11])[CH2:16][CH3:17]Komponenten
4
Versuchsvorschrift
Following the procedure of Example 2 p-menth-3-oyl chloride (2.0 g., 0.01 moles), was reacted with glycine propyl ester hydrochloride (1.5 g., 0.01 moles) and sodium bicarbonate (1.6 g., 0.02 moles). The crude product was distilled b.p. 170°/0.1 mm. (After distillation the product rapidly solidifies). (Found, C: 68.2; H: 1016; N: 5.0. C16H29NO3 requires, C: 67.8; H: 10.6; N: 4.9.)