HCID 53792849, Verbindung → HCID 54044274, Verbindung

HRID 1447960Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1447960
C([N:3]([CH:13]([CH3:15])[CH3:14])[C:4]([C:6]1[NH:7][C:8]([Cl:12])=[C:9]([Cl:11])[N:10]=1)=[O:5])=O>S(=O)(=O)(O)O>[CH:13]([NH:3][C:4]([C:6]1[NH:7][C:8]([Cl:12])=[C:9]([Cl:11])[N:10]=1)=[O:5])([CH3:15])[CH3:14]

Komponenten

3

Edukt 1

HCID 53792849HCID 53792849, Verbindung

Produkt 1

HCID 54044274HCID 54044274, VerbindungAusbeute 72 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel

Versuchsvorschrift

25 g (0.1 mol) of 4,5-dichloro-imidazole-2-carboxylic acid N-formyl-isopropylamide were stirred with 200 ml of concentrated sulphuric acid for about 15 minutes at 50°-70° C. After cooling, the mixture was poured onto ice and the product was filtered off, washed with water until neutral and dried. In this way, 16 g (72% of theory) of 4,5-dichloro-imidazole-2-carboxylic acid isopropylamide with a melting point of 150° C. were obtained.

Aufarbeitung

  1. temperatureAfter cooling
  2. additionthe mixture was poured onto ice
  3. filtrationthe product was filtered off
  4. washwashed with water until neutral and
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-24590ce6ad22449292fd4ba19e9e727a
Quelldatensatz
uspto-grants-1979_12
Patentnummer
US04179277

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