HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl 2-aminobenzoate → 2-chloromethyl-3-(2-ethoxycarbonylphenyl)-6-chloro-4H-quinazolin-4-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl 2-aminobenzoate | HCID 6877 | — |
| Edukt | 5-Chloro-2-((2-chloroacetyl)amino)benzoic acid | HCID 4179825 | — |
| Produkt | 2-chloromethyl-3-(2-ethoxycarbonylphenyl)-6-chloro-4H-quinazolin-4-one | HCID 20375581 | — |
Reaktionsschritte
2-Chloromethyl-3-(2-ethoxycarbonyl-phenyl)-6-chloro-4H-quinazolin-4-one (melting point: 195°-197° C., recrystallised from toluene) was prepared from N-chloroacetyl-5-chloroanthranilic acid and anthranilic acid ethyl ester analogously to the method in J. Amer. Chem. Soc. 68 (1946), 542.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04187306 |
| Quelldatensatz | uspto-grants-1980_02 |
| ORD ID | ord-880d8fc20dcf4ebfae8054a0b1ff3c15 |
| Quellennotiz | uspto-grants-1980_02 |