HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Deuterium Oxide → 3-[[5-[(Acetylhydroxyamino)methyl]tetrahydro-3-furanyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid monosodium salt
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Deuterium Oxide | HCID 24602 | — |
| Edukt | 3-[[5-[[Acetyl(phenylmethoxy)amino]methyl]tetrahydro-3-furanyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monosodium salt | HCID 131719843 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Produkt | 3-[[5-[(Acetylhydroxyamino)methyl]tetrahydro-3-furanyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid monosodium salt | HCID 131719845 | 84,9% |
Reaktionsschritte
A mixture of 0.010 g of product from Example 75, 0.014 g of 10% palladium/carbon, and 1 ml of deuterium oxide is reduced in a Parr apparatus for 2 hours at 30 psi. The reaction solution is filtered and lyophilyzed to give 0.007 g of the desired product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05602118 |
| Quelldatensatz | uspto-grants-1997_02 |
| ORD ID | ord-8ee47fa5cba44378ae4adcb6317f3331 |
| Quellennotiz | uspto-grants-1997_02 |