Hydrochloric Acid → HCID 178479374, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6].[ClH:11].[N:12]#[C:13][NH2:14]>C(O)C>[ClH:11].[NH:1]([C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6])[C:13]([NH2:14])=[NH:12]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 3-aminobenzoic acid (Aldrich, 2.74 g, 0.02 mol), hydrochloric acid (12N, 1.66 g, 0.02 mol), and cyanamide (1.64 g, 0.04 mol) in absolute ethanol (50 mL) was heated at reflux for 16 h. The mixture was cooled and the precipitate separated by filtration. The cake was washed several times with ether and dried under vacuum to give 1.05 g (26.6%) of the title compound as an off-white amorphous powder, mp 278° C.
Aufarbeitung
- temperaturewas heated
- temperatureat reflux for 16 h
- temperatureThe mixture was cooled
- customthe precipitate separated by filtration
- washThe cake was washed several times with ether
- customdried under vacuum
Quellen und Nachweise
- ORD-Eintrag
- ord-61d0e2cc79214452bc663742e726f5a2
- Quelldatensatz
- uspto-grants-1997_02
- Patentnummer
- US05602277
Notizen zur Reaktion
Wird geladen…