Sodium Hydroxide → HCID 14076219, Verbindung

HRID 1451402Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1451402
[C:1]([C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][CH2:15][CH:16]([OH:27])[C:17]2[S:21][C:20]([NH:22][C:23](=[O:25])[CH3:24])=[N:19][C:18]=2[CH3:26])=[CH:8][CH:7]=1)([O:3]CC)=[O:2].[OH-].[Na+]>>[C:1]([C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][NH:14][CH2:15][CH:16]([OH:27])[C:17]2[S:21][C:20]([NH:22][C:23](=[O:25])[CH3:24])=[N:19][C:18]=2[CH3:26])=[CH:8][CH:7]=1)([OH:3])=[O:2]

Komponenten

3

Edukt 2

HCID 14798Sodium HydroxideHCID 14076218HCID 14076218, Verbindung

Produkt 1

HCID 14076219HCID 14076219, Verbindung

Versuchsvorschrift

Prepared analogously to Example 2 by reaction of N-[2-(4-carboethoxyphenyl)ethyl]-2-hydroxy-2-(2-acetylamino-4-methyl-thiazol-5-yl)ethanamine with 1N sodium hydroxide solution. After neutralisation with 1N hydrochloric acid, the mixture is evaporated to dryness, and the residue is recrystallised from 10 ml of water.

Aufarbeitung

  1. customAfter neutralisation with 1N hydrochloric acid, the mixture is evaporated to dryness
  2. customthe residue is recrystallised from 10 ml of water

Quellen und Nachweise

ORD-Eintrag
ord-21ab236f2fcd49ddb3f1fdee9981f9fc
Quelldatensatz
uspto-grants-1997_02
Patentnummer
US05604225

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