HCID 15200703, Verbindung → HCID 19972869, Verbindung

HRID 1451701Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1451701
[CH3:1][N:2]([CH3:27])[C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH:22]=[CH:21][NH:20][C:19]3[C:18](=[O:23])[C:17]4[NH:16][C:15](=[O:24])[CH:14]=[C:13]([CH3:25])[C:12]=4[C:11](=[O:26])[C:10]2=3)=[CH:5][CH:4]=1>C1(C)C(C)=CC=CC=1>[CH3:27][N:2]([CH3:1])[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:22]=[CH:21][N:20]=[C:19]3[C:10]=2[C:11](=[O:26])[C:12]2[C:13]([CH3:25])=[CH:14][C:15](=[O:24])[NH:16][C:17]=2[C:18]3=[O:23])=[CH:5][CH:4]=1

Komponenten

3

Edukt 1

HCID 15200703HCID 15200703, Verbindung

Produkt 1

HCID 19972869HCID 19972869, VerbindungAusbeute 80 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7237O-XyleneLösungsmittel

Versuchsvorschrift

A solution of 25 mg (0.07 mmol) of 3 in xylene (60 ml) was refluxed for 16 hours while air was bubbling through the solution. After evaporation of the solvent, the residue was purified by silica gel chromatography, using ethyl acetate as eluent to yield 20 mg (80%) of 6.

Aufarbeitung

  1. customwas bubbling through the solution
  2. customAfter evaporation of the solvent
  3. customthe residue was purified by silica gel chromatography

Quellen und Nachweise

ORD-Eintrag
ord-91b37fa60f194ae0b03532e900609a18
Quelldatensatz
uspto-grants-1997_02
Patentnummer
US05605905

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