HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(Trifluoromethyl)piperidine → 6-(2-Pentynyloxy)-4-(3-trifluoromethylpiperidino)pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(Trifluoromethyl)piperidine | HCID 2760776 | — |
| Edukt | 4-Chloro-6-(2-pentynyloxy)pyrimidine | HCID 22599770 | — |
| Produkt | 6-(2-Pentynyloxy)-4-(3-trifluoromethylpiperidino)pyrimidine | HCID 66594989 | 47,1% |
Reaktionsschritte
0.2 g of 4-chloro-6-(2-pentynyloxy)pyrimidine and 0.23 g of 3-trifluoromethylpiperidine were mixed and left for 10 hours at room temperature. The reaction mixture was subjected to silica gel column chromatography to obtain 0.15 g of 6-(2-pentynyloxy)-4-(3-trifluoromethylpiperidino)pyrimidine (hereinafter, referred to as Compound (25)).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07732448B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-a070d96be22c454789681963d117bdef |
| Quellennotiz | uspto-grants-2010_06 |