Reaktionsgleichung
[CH2:1]([O:8][C:9]1[C:10]([C:18]([OH:20])=O)=[N:11][NH:12][C:13]=1[C:14]([O:16][CH3:17])=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH:27]([OH:31])[CH2:28][NH:29][CH3:30].N1C=CC=C(C(O)CNC)C=1>>[CH2:1]([O:8][C:9]1[C:13]([C:14]([O:16][CH3:17])=[O:15])=[N:12][NH:11][C:10]=1[C:18]([N:29]([CH2:28][CH:27]([OH:31])[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][N:21]=1)[CH3:30])=[O:20])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Komponenten
4
Versuchsvorschrift
The title compound was prepared from methyl 4-benzyloxy-3-carboxy-1H-pyrazole-5-carboxylate (prepared as in Example 31, Step 1) using a procedure similar to that described in Example 31, Step 2, except that 1-(2-pyridyl)-2-methylaminoethanol (prepared by the methods of Tsushima, S., et al., EP 278621 and Cudahy, M. M., et al., WO 2003059911) was used in place of 1-(3-pyridyl)-2-methylaminoethanol. ES MS (M+1)=410.
Aufarbeitung
- customprepared by the methods of Tsushima, S
Quellen und Nachweise
- ORD-Eintrag
- ord-0439cdb7e8014675a61b1feffbf0df68
- Quelldatensatz
- uspto-grants-2009_01
- Patentnummer
- US07476666B2
Verknüpfte Notizen
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