Sodium Hydroxide → 5-(Methoxymethyl)-6-methylpyridin-2-amine
Reaktionsgleichung
[CH3:1][O:2][CH2:3][C:4]1[CH:5]=[CH:6][C:7]([NH:11]C(=O)C(C)(C)C)=[N:8][C:9]=1[CH3:10].[OH-].[Na+]>>[CH3:1][O:2][CH2:3][C:4]1[CH:5]=[CH:6][C:7]([NH2:11])=[N:8][C:9]=1[CH3:10]Komponenten
3
Versuchsvorschrift
This material was prepared in analogy to example 86 step B) from N-(5-methoxymethyl-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide (0.4 g) and 3M aqueous NaOH (2.68 mL) as a crystalline orange solid (0.174 g). MS (EI): 152.2 (M+).
Quellen und Nachweise
- ORD-Eintrag
- ord-06d3617b524e40e997260002a0a89a23
- Quelldatensatz
- uspto-grants-2009_01
- Patentnummer
- US07482341B2
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