3(S)-(2-((2(S)-Benzoylamino-3-methylbutyryl)benzylamino)acetylamino)-4-oxo-butyric Acid → 3(S)-(2-((2(S)-Benzoylamino-3-methylbutyryl)-(3-aminobenzyl)amino)acetylamino)-4-oxo-butyric Acid

HRID 1456670Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1456670
[C:1]([NH:9][C@@H:10]([CH:32]([CH3:34])[CH3:33])[C:11]([N:13]([CH2:25][C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[CH2:14][C:15]([NH:17][C@H:18]([CH:23]=[O:24])[CH2:19][C:20]([OH:22])=[O:21])=[O:16])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC(=O)C[N:40](C(=O)[C@@H](NC(=O)C1C=CC=CC=1)C(C)C)CC1C=CC=C(NC(OC(C)(C)C)=O)C=1)C>>[C:1]([NH:9][C@@H:10]([CH:32]([CH3:34])[CH3:33])[C:11]([N:13]([CH2:25][C:26]1[CH:27]=[CH:28][CH:29]=[C:30]([NH2:40])[CH:31]=1)[CH2:14][C:15]([NH:17][C@H:18]([CH:23]=[O:24])[CH2:19][C:20]([OH:22])=[O:21])=[O:16])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 544052433(S)-(2-((2(S)-Benzoylamino-3-methylbutyryl)benzylamino)acetylamino)-4-oxo-butyric AcidHCID 54548631((2(S)-Benzoylamino-3-methylbutyryl)-(3-Bocaminobenzyl)amino)acetic Acid Ethyl Ester

Produkt 1

HCID 540672223(S)-(2-((2(S)-Benzoylamino-3-methylbutyryl)-(3-aminobenzyl)amino)acetylamino)-4-oxo-butyric Acid

Versuchsvorschrift

Compound 737 was prepared by a method similar to the method used to prepare compound 706, except compound 703 was replaced with compound 736. ##STR116##

Quellen und Nachweise

ORD-Eintrag
ord-31c357ac5de443d5883aeb800d24aa7b
Quelldatensatz
uspto-grants-1998_12
Patentnummer
US05843904

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