2,2,3,3,3-Pentafluoropropanol → Methyl 2,2,3,3,3-pentafluoropropyl carbonate

Reaktionsgleichung

C([O-])([O-])=O.[K+].[K+].C[O-].[Na+].CO.[F:12][C:13]([F:20])([C:16]([F:19])([F:18])[F:17])[CH2:14][OH:15].[C:21](=O)([O:24]C)[O:22][CH3:23]>>[C:21](=[O:24])([O:15][CH2:14][C:13]([F:20])([F:12])[C:16]([F:19])([F:18])[F:17])[O:22][CH3:23]

Komponenten

Edukt 4

HCID 98722,2,3,3,3-Pentafluoropropanol

HCID 11430Potassium Carbonate

HCID 12021Dimethyl Carbonate

HCID 23694274Sodium methanolate methanol

Produkt 1

HCID 18183634Methyl 2,2,3,3,3-pentafluoropropyl carbonateAusbeute 55 %

Versuchsvorschrift

Methyl 2,2,3,3,3-Pentafluoropropyl carbonate was prepared by the same manner as the example 4 except that K2CO3 (0.046 g) was used as a catalyst in stead of a 28% sodium methoxide/methanol solution (1.3 g). After 2,2,3,3,3-pentafluoropropanol and dimethyl carbonate were allowed to react, the mixture thereof was passed through a column filled with silicagel (8 g) in order to remove K2CO3, and was distilled to give methyl 2,2,3,3,3-pentafluoropropyl carbonate as a colorless liquid (yield 55 %).