HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4,6-Dichloropyrimidine → 4-Chloro-6-(cis-2,6-dimethylpiperidino)pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4,6-Dichloropyrimidine | HCID 70943 | — |
| Edukt | rel-(2R,6S)-2,6-Dimethylpiperidine | HCID 641768 | — |
| Produkt | 4-Chloro-6-(cis-2,6-dimethylpiperidino)pyrimidine | HCID 86607466 | 27,7% |
Reaktionsschritte
0.5 g of 4,6-dichloropyrimidine and 0.76 g of cis-2,6-dimethylpiperidine were mixed and stirred for 10 hours at 90%. The reaction mixture was subjected to silica gel column chromatography to obtain 0.21 g of 4-chloro-6-(cis-2,6-dimethylpiperidino)pyrimidine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07732448B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-f5e9b66fe77449749982e038ebebf7e4 |
| Quellennotiz | uspto-grants-2010_06 |