HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1H-Indole-3-carboxylic acid, 2-chloro- → N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1H-Indole-3-carboxylic acid, 2-chloro- | HCID 99521 | — |
| Edukt | 4-Aminomethyl-1-N-butylpiperidine | HCID 10442133 | — |
| Edukt | N-[(1-n butyl-4-piperidyl)methyl] indole-3-carboxamide | HCID 10591304 | — |
| Produkt | N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamide | HCID 22096969 | — |
Reaktionsschritte
2-Chloroindole-3-carboxylic acid (L. Marchetti and A Andreani, Ann. Chim. (Rome), 1973, 63, 681) was converted to its acid chloride and reacted with N-(1-n butyl-4-piperidyl)methylamine (D 1) using the procedure of Description 1b to afford N-[(1-n butyl-4-piperidyl)methyl] 2-chloroindole-3-carboxamide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05852014 |
| Quelldatensatz | uspto-grants-1998_12 |
| ORD ID | ord-f9cda446b9ad40d18ad12f05a1e650df |
| Quellennotiz | uspto-grants-1998_12 |