Reaktionsgleichung
Cl[C:2]1[C:7]([I:8])=[C:6]([CH2:9][CH3:10])[N:5]=[CH:4][N:3]=1.[CH3:11][Si:12]([CH3:21])([CH3:20])[C@@H:13]1[CH2:18][CH2:17][C@H:16]([NH2:19])[CH2:15][CH2:14]1>>[CH2:9]([C:6]1([NH:19][C@H:16]2[CH2:15][CH2:14][C@@H:13]([Si:12]([CH3:21])([CH3:20])[CH3:11])[CH2:18][CH2:17]2)[NH:5][CH:4]=[N:3][CH:2]=[C:7]1[I:8])[CH3:10]Komponenten
3
Versuchsvorschrift
Prepared as in Example 1 from 4-chloro-5-iodo-6-ethylpyrimidine and cis-4-trimethylsilylcyclohexylamine (yellow oil). The following compounds were further prepared analogously:
Aufarbeitung
- customThe following compounds were further prepared analogously
Quellen und Nachweise
- ORD-Eintrag
- ord-da6d1888eb854afaa6e303296ae5f50e
- Quelldatensatz
- uspto-grants-1998_12
- Patentnummer
- US05852023
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