Acetyl chloride → 2,3-Dimethylsuccinic anhydride

HRID 1459691

Reaktionsgleichung

Reaktionsgleichung von HRID 1459691
[CH3:1][CH:2]([CH:6]([CH3:10])[C:7]([OH:9])=[O:8])[C:3](O)=[O:4].C(Cl)(=O)C>>[CH3:1][CH:2]1[CH:6]([CH3:10])[C:7](=[O:9])[O:8][C:3]1=[O:4]

Komponenten

3

Edukt 2

HCID 6367Acetyl chlorideHCID 118482,3-Dimethylsuccinic acid

Produkt 1

HCID 1401452,3-Dimethylsuccinic anhydride

Reaktionsbedingungen

Temperatur
65 °C

Versuchsvorschrift

To the 2,3-dimethyl succinic acid (5.13 g, 35.1 mmol), was added acetyl chloride (8.27 g, 7.49 mL, 105 mmol) at room temperature. The reaction mixture was refluxed at about 65° C. for 2 hrs. Workup consisted of concentration in vacuo, and drying in high vacuo. The desired product (4.95 g, with a little impurity of acetic acid) was obtained as a white solid.

Aufarbeitung

  1. concentrationWorkup consisted of concentration in vacuo
  2. customdrying in high vacuo

Quellen und Nachweise

ORD-Eintrag
ord-e455c41522a846f1b104a6b5de56e2d1
Quelldatensatz
uspto-grants-1998_12
Patentnummer
US05854277

Verknüpfte Notizen

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